About This Book
Supramolecular Chemistry is the study of non-covalent interactions between molecules, which allows
them to form larger, more complex structures. Unlike traditional chemistry, which focuses on covalent
bonds between atoms, supramolecular chemistry examines the interactions between molecules
through weaker forces, such as hydrogen bonding, van der Waals forces, ?-? stacking, and ionic
interactions. These interactions enable the formation of molecular complexes and assemblies with
unique properties and functions. One of the core ideas in supramolecular chemistry is the concept of
host-guest chemistry, where one molecule (the host) selectively binds to another molecule (the guest)
through non-covalent interactions. This principle has led to the development of molecular recognition,
where specific molecules can be identified and selectively bound, akin to how enzymes recognize their
substrates. The design of synthetic hosts that can encapsulate and release guest molecules has
applications in drug delivery, catalysis, and sensor technologies. Supramolecular chemistry has also
contributed to the development of self-assembly processes, where molecules spontaneously organize
themselves into well-defined structures without the need for external intervention. This self-assembly is
used in creating nanomaterials, molecular machines, and stimuli-responsive systems. The versatility of
supramolecular chemistry in creating diverse, functional structures makes it an essential field for
advancing molecular design and technology in areas like materials science, nanotechnology, and
biochemistry.
Contents: 1. Molecular Modeling and Computational Chemistry, 2. Lewis Structures of Molecules,
3. Molecular Structure, 4. Catalysis in Organic Synthesis: Mechanisms and Innovations, 5. Molecular
Vibrations and Coordinates, 6. Advances in Drug Synthesis and the Challenge of Antibiotic Resistance,
7. Supramolecular Catalysis and Mechanisms, 8. Pharmacodynamics and the Role of Drug-Receptor
Binding, 9. Analysis and Synthesis of Molecular Machines.